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KMID : 0377619760310050505
Korean Jungang Medical Journal
1976 Volume.31 No. 5 p.505 ~ p.512
A Clinical Study of Plasma Substitute Solution(Volex). (Report No. 2)


Abstract
The five different plasma substitute solutions of volex, dextrane 40 in glucose, dextrane 70 in glucose, ringer lactate, and 5% glucose were comparatively examined in 10-40 cases (132 cases in total) with the statistical method. The results showed that the intravascular retention rate in the immediate postoperative circulatory dynamics was maximum in dext. 70 in glucose, followed by dext. 40 in glucose, that of volex was between, dext. 40 in glucose Hemodilution occured as a matter of course at any cases, but was low in volex among them. In most cases plasma electrolytes remind within the normal range, except, the elevation tendency of pottasium in volex and dext. 40.
As to the renal functions with our infusion method using these plasma substitutes, the increase of urine volume and the reduction of BUN were observed especially on the second postoperative day. From the viewpoint of clinical hemorheology, the elevation of errythrocyte sedimentation rate was prominent in dext. 70, and little in dext. 40 and volex. Then, it can be suggested that volex was efficient to keep the microcirculation of the blood. Besides a pseudoaggutination observed in one of the cases with dext. 70 in glucose, which made an error in. blood typing nothing abnormal was observed in other groups.
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